Brilliant Sophia, 35, has just completed her doctorate. Unfortunately, she does not succeed in obtaining the position to which she aspired at university. She therefore finds herself unemployed. She then moves to her brother, Karim, an inveterate seducer. Both unmarried, they have a fusional, close and codependent relationship that seems indestructible. Things get complicated when he falls madly in love with Eloïse, Sophia's pretty gynecologist.